| Protein Name | C-terminal binding protein 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1487 |
| Gene Symbol | CTBP1 |
| UniProt | Q13363 (CTBP1_HUMAN), X5D8Y5 (X5D8Y5_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
51
Total Number of Articles : 60 |
Description |
C-terminal binding protein 1 |
| Gene Summary |
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
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| Properties | |