CPRiL

Protein Name	hydroxysteroid 17-beta dehydrogenase 10
Organism	Homo sapiens
Gene ID	3028
Gene Symbol	HSD17B10
UniProt	Q99714 (HCD2_HUMAN), A0A0S2Z410 (A0A0S2Z410_HUMAN)
Relationships	Total Number of functionally related compound(s) : 95 Total Number of Articles : 61
Description	hydroxysteroid 17-beta dehydrogenase 10
Gene Summary	This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014]
synonyms	3-hydroxyacyl-CoA dehydrogenase type-2 3-hydroxy-2-methylbutyryl-CoA dehydrogenase AB-binding alcohol dehydrogenase amyloid-beta peptide binding alcohol dehydrogenase endoplasmic reticulum-associated amyloid beta-peptide-binding protein mitochondrial RNase P subunit 2 mitochondrial ribonuclease P protein 2 short chain L-3-hydroxyacyl-CoA dehydrogenase type 2 short chain type dehydrogenase/reductase XH98G2 17b-HSD10 ABAD CAMR DUPXp11.22 ERAB HADH2 HCD2 HSD10MD MHBD MRPP2 MRX17 MRX31 MRXS10 SCHAD SDR5C1 Click to show/hide the synonyms
Properties