Protein Name hexokinase 1
Organism Mus musculus
Gene ID 15275
Gene Symbol

Hk1

UniProt P17710 (HXK1_MOUSE), B4YB29 (B4YB29_MOUSE), G3UVV4 (G3UVV4_MOUSE), Q6GQU1 (Q6GQU1_MOUSE), Q3TTB4 (Q3TTB4_MOUSE)
Relationships Total Number of functionally related compound(s) : 41
Total Number of Articles : 44
Description

hexokinase 1

Gene Summary

Enables glucokinase activity and peptidoglycan binding activity. Involved in carbohydrate phosphorylation; hexose metabolic process; and positive regulation of cytokine production. Located in cytosol; membrane raft; and mitochondrion. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4G; anemia (multiple); hematologic cancer (multiple); obesity; and retinitis pigmentosa (multiple). Orthologous to human HK1 (hexokinase 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • hexokinase-1
  • HK I
  • downeast anemia
Click to show/hide the synonyms
Properties