Protein Name somatostatin
Organism Homo sapiens
Gene ID 6750
Gene Symbol


UniProt P61278 (SMS_HUMAN)
Relationships Total Number of functionally related compound(s) : 539
Total Number of Articles : 877


Gene Summary

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]

  • somatostatin
  • growth hormone release-inhibiting factor
  • prepro-somatostatin
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