Protein Name grancalcin
Organism Homo sapiens
Gene ID 25801
Gene Symbol

GCA

UniProt P28676 (GRAN_HUMAN), H7BXD5 (H7BXD5_HUMAN), B7Z322 (B7Z322_HUMAN)
Relationships Total Number of functionally related compound(s) : 41
Total Number of Articles : 42
Description

grancalcin

Gene Summary

This gene encodes a calcium-binding protein that is abundant in neutrophils and macrophages. In the absence of divalent cation, this protein localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions. Alternative splicing and use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Aug 2016]

synonyms
  • grancalcin
  • grancalcin, EF-hand calcium-binding protein
  • grancalcin, penta-EF-hand protein
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Properties