Protein Name hydroxysteroid 17-beta dehydrogenase 3
Organism Homo sapiens
Gene ID 3293
Gene Symbol

HSD17B3

UniProt P37058 (DHB3_HUMAN), Q6FH62 (Q6FH62_HUMAN)
Relationships Total Number of functionally related compound(s) : 71
Total Number of Articles : 82
Description

hydroxysteroid 17-beta dehydrogenase 3

Gene Summary

This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]

synonyms
  • 17-beta-hydroxysteroid dehydrogenase type 3
  • 17-beta-HSD 3
  • 17-beta-HSD3
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Properties