Protein Name growth hormone receptor
Organism Mus musculus
Gene ID 14600
Gene Symbol

Ghr

UniProt P16882 (GHR_MOUSE), Q3UP14 (Q3UP14_MOUSE), Q3UNY8 (Q3UNY8_MOUSE)
Relationships Total Number of functionally related compound(s) : 89
Total Number of Articles : 109
Description

growth hormone receptor

Gene Summary

Enables growth hormone receptor activity and peptide hormone binding activity. Involved in growth hormone receptor signaling pathway via JAK-STAT and regulation of growth. Acts upstream of with a positive effect on taurine metabolic process. Located in nucleus and plasma membrane. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and integumental system. Used to study Laron syndrome. Human ortholog(s) of this gene implicated in several diseases, including Laron syndrome; familial hypercholesterolemia; isolated growth hormone deficiency; osteoarthritis; and type 2 diabetes mellitus. Orthologous to human GHR (growth hormone receptor). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • growth hormone receptor
  • GH receptor
  • Growth hormone receptor precursor (GH receptor) (GH binding protein) (GHBP) (Serum binding protein)
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Properties