Protein Name | DCC netrin 1 receptor |
---|---|
Organism | Mus musculus |
Gene ID | 13176 |
Gene Symbol | Dcc |
UniProt | P70211 (DCC_MOUSE), Q3TZP5 (Q3TZP5_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
43
Total Number of Articles : 44 |
Description |
DCC netrin 1 receptor |
Gene Summary |
Predicted to enable identical protein binding activity; netrin receptor activity; and transcription coactivator activity. Involved in postsynaptic modulation of chemical synaptic transmission. Acts upstream of or within generation of neurons. Located in axon. Is active in Schaffer collateral - CA1 synapse and postsynaptic density membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; lung; and retina. Used to study essential thrombocythemia and polycythemia vera. Human ortholog(s) of this gene implicated in colorectal cancer; congenital mirror movement disorder; and esophagus squamous cell carcinoma. Orthologous to human DCC (DCC netrin 1 receptor). [provided by Alliance of Genome Resources, Jul 2025] |
synonyms |
|
Properties | |