Protein Name DCC netrin 1 receptor
Organism Mus musculus
Gene ID 13176
Gene Symbol

Dcc

UniProt P70211 (DCC_MOUSE), Q3TZP5 (Q3TZP5_MOUSE)
Relationships Total Number of functionally related compound(s) : 43
Total Number of Articles : 44
Description

DCC netrin 1 receptor

Gene Summary

Predicted to enable identical protein binding activity; netrin receptor activity; and transcription coactivator activity. Involved in postsynaptic modulation of chemical synaptic transmission. Acts upstream of or within generation of neurons. Located in axon. Is active in Schaffer collateral - CA1 synapse and postsynaptic density membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; lung; and retina. Used to study essential thrombocythemia and polycythemia vera. Human ortholog(s) of this gene implicated in colorectal cancer; congenital mirror movement disorder; and esophagus squamous cell carcinoma. Orthologous to human DCC (DCC netrin 1 receptor). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • netrin receptor DCC
  • deleted in colorectal carcinoma
  • tumor suppressor protein DCC
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Properties