| Protein Name | complement component 1, r subcomponent A |
|---|---|
| Organism | Mus musculus |
| Gene ID | 50909 |
| Gene Symbol | C1ra |
| UniProt | Q8CG16 (C1RA_MOUSE), Q9CTX0 (Q9CTX0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
2
Total Number of Articles : 2 |
Description |
complement component 1, r subcomponent A |
| Gene Summary |
Predicted to enable several functions, including calcium ion binding activity; identical protein binding activity; and serine-type endopeptidase activity. Predicted to be involved in complement activation, classical pathway and zymogen activation. Predicted to act upstream of or within several processes, including activation of membrane attack complex; killing of cells of another organism; and opsonization. Predicted to be located in cell surface and extracellular region. Predicted to be part of complement component C1 complex. Predicted to be active in blood microparticle and symbiont cell surface. Is expressed in several structures, including adrenal gland; genitourinary system; hemolymphoid system gland; midbrain; and small intestine. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome periodontal type 1. Orthologous to human C1R (complement C1r). [provided by Alliance of Genome Resources, Jul 2025] |
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