| Protein Name | RAD21 cohesin complex component |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 5885 |
| Gene Symbol | RAD21 |
| UniProt | O60216 (RAD21_HUMAN), A0A024R9J0 (A0A024R9J0_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
51
Total Number of Articles : 45 |
Description |
RAD21 cohesin complex component |
| Gene Summary |
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008] |
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