Protein Name plexin A2
Organism Homo sapiens
Gene ID 5362
Gene Symbol


UniProt O75051 (PLXA2_HUMAN)
Relationships Total Number of functionally related compound(s) : 461
Total Number of Articles : 598

plexin A2

Gene Summary

This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008]

  • plexin-A2
  • plexin 2
  • semaphorin receptor OCT
Click to show/hide the synonyms