| Protein Name | plexin A2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 5362 |
| Gene Symbol | PLXNA2 |
| UniProt | O75051 (PLXA2_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
461
Total Number of Articles : 598 |
Description |
plexin A2 |
| Gene Summary |
This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008] |
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| Properties | |