| Protein Name | 5-methyltetrahydrofolate-homocysteine methyltransferase |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 81522 |
| Gene Symbol | Mtr |
| UniProt | Q9Z2Q4 (METH_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
48
Total Number of Articles : 58 |
Description |
5-methyltetrahydrofolate-homocysteine methyltransferase |
| Gene Summary |
Enables amino acid binding activity; folic acid binding activity; and methionine synthase activity. Involved in several processes, including cellular response to methionine; cellular response to nitric oxide; and sulfur amino acid metabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Biomarker of fetal alcohol spectrum disorder; type 2 diabetes mellitus; and vitamin B12 deficiency. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); autistic disorder; hematologic cancer (multiple); and hyperhomocysteinemia. Orthologous to human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |