Protein Name | Yes1 associated transcriptional regulator |
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Organism | Rattus norvegicus |
Gene ID | 363014 |
Gene Symbol | Yap1 |
UniProt | Q2EJA0 (YAP1_RAT) |
Relationships |
Total Number of functionally related compound(s) :
77
Total Number of Articles : 73 |
Description |
Yes1 associated transcriptional regulator |
Gene Summary |
Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; proline-rich region binding activity; and transcription coregulator activity. Predicted to be involved in several processes, including cardiac muscle tissue regeneration; intracellular signal transduction; and regulation of gene expression. Predicted to act upstream of or within several processes, including regulation of epithelial cell differentiation; regulation of epithelial cell proliferation; and tube morphogenesis. Predicted to be located in several cellular components, including mitochondrion; nucleus; and tight junction. Predicted to be part of TEAD-YAP complex. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in uveal coloboma-cleft lip and palate-intellectual disability. Orthologous to human YAP1 (Yes1 associated transcriptional regulator). [provided by Alliance of Genome Resources, Jun 2025] |
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