Protein Name Yes1 associated transcriptional regulator
Organism Rattus norvegicus
Gene ID 363014
Gene Symbol

Yap1

UniProt Q2EJA0 (YAP1_RAT)
Relationships Total Number of functionally related compound(s) : 77
Total Number of Articles : 73
Description

Yes1 associated transcriptional regulator

Gene Summary

Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; proline-rich region binding activity; and transcription coregulator activity. Predicted to be involved in several processes, including cardiac muscle tissue regeneration; intracellular signal transduction; and regulation of gene expression. Predicted to act upstream of or within several processes, including regulation of epithelial cell differentiation; regulation of epithelial cell proliferation; and tube morphogenesis. Predicted to be located in several cellular components, including mitochondrion; nucleus; and tight junction. Predicted to be part of TEAD-YAP complex. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in uveal coloboma-cleft lip and palate-intellectual disability. Orthologous to human YAP1 (Yes1 associated transcriptional regulator). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • transcriptional coactivator YAP1
  • 65 kDa Yes-associated protein
  • protein yorkie homolog
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Properties