Protein Name neuroblastoma ras oncogene
Organism Mus musculus
Gene ID 18176
Gene Symbol

Nras

UniProt Q9D091 (Q9D091_MOUSE), Q3TMF4 (Q3TMF4_MOUSE), Q4FJP3 (Q4FJP3_MOUSE)
Relationships Total Number of functionally related compound(s) : 68
Total Number of Articles : 72
Description

neuroblastoma ras oncogene

Gene Summary

Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in positive regulation of angiogenesis. Acts upstream of or within several processes, including T cell receptor signaling pathway; defense response to protozoan; and positive regulation of type II interferon production. Located in membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and genitourinary system. Used to study skin melanoma. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 6; autoimmune lymphoproliferative syndrome type 4; endocrine gland cancer (multiple); hematologic cancer (multiple); and reproductive organ cancer (multiple). Orthologous to human NRAS (NRAS proto-oncogene, GTPase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • GTPase NRas
  • transforming protein N-Ras
  • N-ras
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Properties