Protein Name B lymphoid kinase
Organism Mus musculus
Gene ID 12143
Gene Symbol

Blk

UniProt P16277 (BLK_MOUSE)
Relationships Total Number of functionally related compound(s) : 9
Total Number of Articles : 12
Description

B lymphoid kinase

Gene Summary

Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; peptidyl-tyrosine phosphorylation; and positive regulation of insulin secretion. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Is expressed in several structures, including 2-cell stage embryo; central nervous system; ileum; male reproductive gland or organ; and peripheral nervous system. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 11 and systemic lupus erythematosus. Orthologous to human BLK (BLK proto-oncogene, Src family tyrosine kinase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • tyrosine-protein kinase Blk
  • b lymphocyte kinase
  • p55-Blk
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Properties