Protein Name midkine
Organism Homo sapiens
Gene ID 4192
Gene Symbol

MDK

UniProt P21741 (MK_HUMAN)
Relationships Total Number of functionally related compound(s) : 106
Total Number of Articles : 150
Description

midkine

Gene Summary

This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

synonyms
  • midkine
  • amphiregulin-associated protein
  • midgestation and kidney protein
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Properties