Protein Name crystallin zeta
Organism Homo sapiens
Gene ID 1429
Gene Symbol


UniProt Q08257 (QOR_HUMAN)
Relationships Total Number of functionally related compound(s) : 167
Total Number of Articles : 246

crystallin zeta

Gene Summary

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]

  • quinone oxidoreductase
  • NADPH:quinone reductase
  • crystallin, zeta (quinone reductase)
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