Protein Name catenin alpha 2
Organism Mus musculus
Gene ID 12386
Gene Symbol

Ctnna2

UniProt Q61301 (CTNA2_MOUSE)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 5
Description

catenin alpha 2

Gene Summary

Enables identical protein binding activity. Involved in several processes, including modification of postsynaptic actin cytoskeleton; nervous system development; and prepulse inhibition. Located in several cellular components, including adherens junction; basolateral plasma membrane; and postsynaptic density. Is active in several cellular components, including hippocampal mossy fiber to CA3 synapse; parallel fiber to Purkinje cell synapse; and postsynaptic density, intracellular component. Is extrinsic component of postsynaptic membrane and extrinsic component of presynaptic membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Orthologous to human CTNNA2 (catenin alpha 2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • catenin alpha-2
  • alpha(N)-catenin
  • cadherin associated protein
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Properties