Protein Name | catenin alpha 2 |
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Organism | Mus musculus |
Gene ID | 12386 |
Gene Symbol | Ctnna2 |
UniProt | Q61301 (CTNA2_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
8
Total Number of Articles : 5 |
Description |
catenin alpha 2 |
Gene Summary |
Enables identical protein binding activity. Involved in several processes, including modification of postsynaptic actin cytoskeleton; nervous system development; and prepulse inhibition. Located in several cellular components, including adherens junction; basolateral plasma membrane; and postsynaptic density. Is active in several cellular components, including hippocampal mossy fiber to CA3 synapse; parallel fiber to Purkinje cell synapse; and postsynaptic density, intracellular component. Is extrinsic component of postsynaptic membrane and extrinsic component of presynaptic membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Orthologous to human CTNNA2 (catenin alpha 2). [provided by Alliance of Genome Resources, Jun 2025] |
synonyms |
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Properties | |