Protein Name | EPH receptor A3 |
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Organism | Homo sapiens |
Gene ID | 2042 |
Gene Symbol | EPHA3 |
UniProt | P29320 (EPHA3_HUMAN), A0A140VJJ0 (A0A140VJJ0_HUMAN), C9JXA2 (C9JXA2_HUMAN), Q6P4R6 (Q6P4R6_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
95
Total Number of Articles : 69 |
Description |
EPH receptor A3 |
Gene Summary |
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008] |
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Properties | |