| Protein Name | proline dehydrogenase 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 5625 |
| Gene Symbol | PRODH |
| UniProt | O43272 (PROD_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
121
Total Number of Articles : 124 |
Description |
proline dehydrogenase 1 |
| Gene Summary |
This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010] |
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| Properties | |