| Protein Name | dopamine receptor D1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13488 |
| Gene Symbol | Drd1 |
| UniProt | Q61616 (DRD1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
233
Total Number of Articles : 524 |
Description |
dopamine receptor D1 |
| Gene Summary |
Enables G protein-coupled receptor activity and dopamine neurotransmitter receptor activity, coupled via Gs. Involved in adenylate cyclase-activating dopamine receptor signaling pathway; modification of postsynaptic structure; and presynaptic modulation of chemical synaptic transmission. Acts upstream of or within several processes, including central nervous system development; learning or memory; and modulation of chemical synaptic transmission. Located in several cellular components, including dendritic spine; endoplasmic reticulum; and nucleus. Is active in GABA-ergic synapse; glutamatergic synapse; and synaptic membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Used to study Huntington's disease. Human ortholog(s) of this gene implicated in hypertension and kidney failure. Orthologous to human DRD1 (dopamine receptor D1). [provided by Alliance of Genome Resources, Jun 2025] |
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