Protein Name tinman
Organism Drosophila melanogaster
Gene ID 42536
Gene Symbol

tin

UniProt P22711 (TIN_DROME), B6IDS0 (B6IDS0_DROME)
Relationships Total Number of functionally related compound(s) : 42
Total Number of Articles : 48
Description

tinman

Gene Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including digestive tract development; gonadal mesoderm development; and heart development. Located in nucleus. Is expressed in several structures, including adult heart; cardiogenic mesoderm; dorsal vessel; dorsal vessel wall cell; and pericardial cell. Used to study congenital heart disease. Orthologous to human NKX2-2 (NK2 homeobox 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • tinman
  • CG7895-PA
  • muscle-specific-homeodomain-2
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Properties