Protein Name linker for activation of T cells
Organism Rattus norvegicus
Gene ID 81511
Gene Symbol

Lat

UniProt O70601 (LAT_RAT)
Relationships Total Number of functionally related compound(s) : 37
Total Number of Articles : 30
Description

linker for activation of T cells

Gene Summary

Predicted to enable molecular condensate scaffold activity; protein kinase binding activity; and signaling receptor complex adaptor activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; intracellular signaling cassette; and membrane raft distribution. Predicted to act upstream of or within gene expression and lymphocyte homeostasis. Predicted to be located in Golgi apparatus; cell-cell junction; and membrane. Predicted to be part of COP9 signalosome and TCR signalosome. Predicted to be active in immunological synapse. Human ortholog(s) of this gene implicated in immunodeficiency 52. Orthologous to human LAT (linker for activation of T cells). [provided by Alliance of Genome Resources, Apr 2025]

synonyms
  • linker for activation of T-cells family member 1
  • 36 kDa phospho-tyrosine adapter protein
  • 36 kDa phosphotyrosine adapter protein
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Properties