Protein Name | 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog |
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Organism | Xenopus laevis |
Gene ID | 397750 |
Gene Symbol | hmgcr.L |
UniProt | P20715 (HMDH_XENLA) |
Relationships |
Total Number of functionally related compound(s) :
2
Total Number of Articles : 2 |
Description |
3-hydroxy-3-methylglutaryl-CoA reductase L homeolog |
Gene Summary |
Predicted to enable NADP binding activity and hydroxymethylglutaryl-CoA reductase (NADPH) activity. Predicted to act upstream of or within cholesterol biosynthetic process; coenzyme A metabolic process; and isoprenoid biosynthetic process. Predicted to be located in endoplasmic reticulum and peroxisomal membrane. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; coronary artery disease (multiple); diabetes mellitus (multiple); muscular disease (multiple); and neurodegenerative disease (multiple). Orthologous to human HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). [provided by Alliance of Genome Resources, Jul 2025] |
synonyms |
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Properties | |