Protein Name 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog
Organism Xenopus laevis
Gene ID 397750
Gene Symbol

hmgcr.L

UniProt P20715 (HMDH_XENLA)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 2
Description

3-hydroxy-3-methylglutaryl-CoA reductase L homeolog

Gene Summary

Predicted to enable NADP binding activity and hydroxymethylglutaryl-CoA reductase (NADPH) activity. Predicted to act upstream of or within cholesterol biosynthetic process; coenzyme A metabolic process; and isoprenoid biosynthetic process. Predicted to be located in endoplasmic reticulum and peroxisomal membrane. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; coronary artery disease (multiple); diabetes mellitus (multiple); muscular disease (multiple); and neurodegenerative disease (multiple). Orthologous to human HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • 3-hydroxy-3-methylglutaryl-coenzyme A reductase
  • HMG-CoA reductase
  • XELAEV_18008167mg
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Properties