Protein Name uridine monophosphate synthetase
Organism Mus musculus
Gene ID 22247
Gene Symbol

Umps

UniProt P13439 (UMPS_MOUSE), Q544K9 (Q544K9_MOUSE)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 9
Description

uridine monophosphate synthetase

Gene Summary

Enables orotate phosphoribosyltransferase activity and orotidine-5'-phosphate decarboxylase activity. Involved in 'de novo' UMP biosynthetic process and UDP biosynthetic process. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; limb bud; metanephros; pancreas; and surface ectoderm. Human ortholog(s) of this gene implicated in orotic aciduria and purine-pyrimidine metabolic disorder. Orthologous to human UMPS (uridine monophosphate synthetase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • uridine 5'-monophosphate synthase
  • UMP synthase
  • 1700095D23Rik
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Properties