Protein Name calcium voltage-gated channel subunit alpha1 E
Organism Homo sapiens
Gene ID 777
Gene Symbol

CACNA1E

UniProt Q15878 (CAC1E_HUMAN), Q59FG1 (Q59FG1_HUMAN)
Relationships Total Number of functionally related compound(s) : 88
Total Number of Articles : 76
Description

calcium voltage-gated channel subunit alpha1 E

Gene Summary

Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]

synonyms
  • voltage-dependent R-type calcium channel subunit alpha-1E
  • brain calcium channel II
  • calcium channel, L type, alpha-1 polypeptide
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Properties