| Protein Name | neogenin 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 4756 |
| Gene Symbol | NEO1 |
| UniProt | Q92859 (NEO1_HUMAN), Q59FP8 (Q59FP8_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
30
Total Number of Articles : 34 |
Description |
neogenin 1 |
| Gene Summary |
This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] |
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| Properties | |