Protein Name microtubule affinity regulating kinase 2
Organism Homo sapiens
Gene ID 2011
Gene Symbol

MARK2

UniProt Q7KZI7 (MARK2_HUMAN), E7ETY4 (E7ETY4_HUMAN), A0A140VJP1 (A0A140VJP1_HUMAN), A8K2S4 (A8K2S4_HUMAN)
Relationships Total Number of functionally related compound(s) : 29
Total Number of Articles : 40
Description

microtubule affinity regulating kinase 2

Gene Summary

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]

synonyms
  • serine/threonine-protein kinase MARK2
  • ELKL motif kinase 1
  • MAP/microtubule affinity-regulating kinase 2
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Properties