CPRiL

Protein Name	splicing factor proline and glutamine rich
Organism	Homo sapiens
Gene ID	6421
Gene Symbol	SFPQ
UniProt	P23246 (SFPQ_HUMAN), A0A384N5Z8 (A0A384N5Z8_HUMAN), Q86VG2 (Q86VG2_HUMAN)
Relationships	Total Number of functionally related compound(s) : 67 Total Number of Articles : 73
Description	splicing factor proline and glutamine rich
Gene Summary	Enables DNA binding activity; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; and regulation of transcription by RNA polymerase II. Acts upstream of or within double-strand break repair via homologous recombination. Located in chromatin; nuclear matrix; and paraspeckles. [provided by Alliance of Genome Resources, Apr 2022]
synonyms	splicing factor, proline- and glutamine-rich 100 kDa DNA-pairing protein DNA-binding p52/p100 complex, 100 kDa subunit PTB-associated splicing factor epididymis secretory sperm binding protein polypyrimidine tract binding protein associated polypyrimidine tract-binding protein-associated splicing factor protein phosphatase 1, regulatory subunit 140 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) splicing factor proline/glutamine-rich POMP100 PPP1R140 PSF Click to show/hide the synonyms
Properties