| Protein Name | leptin |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25608 |
| Gene Symbol | Lep |
| UniProt | P50596 (LEP_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
693
Total Number of Articles : 1106 |
Description |
leptin |
| Gene Summary |
Enables hormone activity and peptide hormone receptor binding activity. Involved in several processes, including positive regulation of cell communication; positive regulation of metabolic process; and regulation of apoptotic process. Located in cytosol and extracellular space. Used to study several diseases, including alcohol dependence; glucose metabolism disease (multiple); liver disease (multiple); neurodegenerative disease (multiple); and short bowel syndrome. Biomarker of several diseases, including Huntington's disease; alcohol dependence; lipid metabolism disorder (multiple); liver disease (multiple); and obesity. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; congenital leptin deficiency; liver disease (multiple); lung disease (multiple); and type 2 diabetes mellitus. Orthologous to human LEP (leptin). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |