Protein Name amelogenin, X-linked
Organism Mus musculus
Gene ID 11704
Gene Symbol

Amelx

UniProt P63277 (AMELX_MOUSE), Q6PCW7 (Q6PCW7_MOUSE), R9W2T8 (R9W2T8_MOUSE)
Relationships Total Number of functionally related compound(s) : 35
Total Number of Articles : 23
Description

amelogenin, X-linked

Gene Summary

Enables several functions, including growth factor activity; hydroxyapatite binding activity; and metal ion binding activity. Involved in cell adhesion; enamel mineralization; and regulation of cell population proliferation. Located in basement membrane and cell surface. Part of protein-containing complex. Is expressed in several structures, including connective tissue; eye; jaw; nervous system; and skeleton. Used to study amelogenesis imperfecta type 1E. Human ortholog(s) of this gene implicated in amelogenesis imperfecta and amelogenesis imperfecta type 1E. Orthologous to several human genes including AMELX (amelogenin X-linked). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • amelogenin, X isoform
  • amelogenin X chromosome
  • enamel matrix protein
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Properties