Protein Name dolichol kinase
Organism Homo sapiens
Gene ID 22845
Gene Symbol

DOLK

UniProt Q9UPQ8 (DOLK_HUMAN), A0A0S2Z597 (A0A0S2Z597_HUMAN)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 7
Description

dolichol kinase

Gene Summary

The protein encoded by this gene catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.[provided by RefSeq, Apr 2010]

synonyms
  • dolichol kinase
  • SEC59 homolog
  • dolichol kinase 1
Click to show/hide the synonyms
Properties