| Protein Name | prolactin receptor |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19116 |
| Gene Symbol | Prlr |
| UniProt | Q08501 (PRLR_MOUSE), G3UVW6 (G3UVW6_MOUSE), Q8C5N1 (Q8C5N1_MOUSE), Q3TNP6 (Q3TNP6_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
40
Total Number of Articles : 59 |
Description |
prolactin receptor |
| Gene Summary |
Enables prolactin receptor activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cell surface receptor signaling pathway via JAK-STAT; mammary gland development; and prostate gland growth. Predicted to be located in cell surface. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and limb segment. Used to study familial medullary thyroid carcinoma. Human ortholog(s) of this gene implicated in hyperprolactinemia. Orthologous to human PRLR (prolactin receptor). [provided by Alliance of Genome Resources, Jun 2025] |
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