Protein Name heat shock transcription factor 1
Organism Rattus norvegicus
Gene ID 79245
Gene Symbol

Hsf1

UniProt F1MAF1 (F1MAF1_RAT)
Relationships Total Number of functionally related compound(s) : 66
Total Number of Articles : 61
Description

heat shock transcription factor 1

Gene Summary

Enables several functions, including STAT family protein binding activity; promoter-specific chromatin binding activity; and sequence-specific single stranded DNA binding activity. Involved in several processes, including cellular response to lipid; positive regulation of macromolecule metabolic process; and regulation of inclusion body assembly. Located in chromatin; cytoplasm; and nucleus. Used to study Parkinson's disease; muscular atrophy; and transient cerebral ischemia. Biomarker of Alzheimer's disease; Parkinson's disease; congestive heart failure; cryptorchidism; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to human HSF1 (heat shock transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • heat shock factor protein 1
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Properties