| Protein Name | heat shock transcription factor 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 79245 |
| Gene Symbol | Hsf1 |
| UniProt | F1MAF1 (F1MAF1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
66
Total Number of Articles : 61 |
Description |
heat shock transcription factor 1 |
| Gene Summary |
Enables several functions, including STAT family protein binding activity; promoter-specific chromatin binding activity; and sequence-specific single stranded DNA binding activity. Involved in several processes, including regulation of apoptotic process; regulation of inclusion body assembly; and regulation of macromolecule metabolic process. Located in euchromatin and heterochromatin. Used to study Parkinson's disease; muscular atrophy; and transient cerebral ischemia. Biomarker of Alzheimer's disease; Parkinson's disease; congestive heart failure; cryptorchidism; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to human HSF1 (heat shock transcription factor 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |