| Protein Name | high mobility group box 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 97165 |
| Gene Symbol | Hmgb2 |
| UniProt | P30681 (HMGB2_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
12
Total Number of Articles : 9 |
Description |
high mobility group box 2 |
| Gene Summary |
Enables DNA-binding transcription factor binding activity; cis-regulatory region sequence-specific DNA binding activity; and protein domain specific binding activity. Involved in several processes, including regulation of gene expression; regulation of stem cell proliferation; and response to lipopolysaccharide. Acts upstream of or within several processes, including male gonad development; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and spermatid nucleus differentiation. Located in several cellular components, including chromatin; extracellular space; and nucleus. Is expressed in several structures, including alimentary system; brain; branchial arch; retina; and urinary system. Orthologous to human HMGB2 (high mobility group box 2). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |