Protein Name glutamic-oxaloacetic transaminase 2
Organism Rattus norvegicus
Gene ID 25721
Gene Symbol

Got2

UniProt P00507 (AATM_RAT)
Relationships Total Number of functionally related compound(s) : 869
Total Number of Articles : 1329
Description

glutamic-oxaloacetic transaminase 2

Gene Summary

Enables several functions, including L-aspartate:2-oxoglutarate aminotransferase activity; anion binding activity; and identical protein binding activity. Involved in several processes, including dicarboxylic acid metabolic process; lactation; and response to morphine. Located in several cellular components, including T-tubule; mitochondrial inner membrane; and perikaryon. Part of protein-containing complex. Biomarker of acute kidney failure; neurodegenerative disease; obesity; and schizophrenia. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 82. Orthologous to human GOT2 (glutamic-oxaloacetic transaminase 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • aspartate aminotransferase, mitochondrial
  • FABP-1
  • FABPpm
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Properties