Protein Name frizzled class receptor 4
Organism Homo sapiens
Gene ID 8322
Gene Symbol

FZD4

UniProt Q9ULV1 (FZD4_HUMAN)
Relationships Total Number of functionally related compound(s) : 25
Total Number of Articles : 28
Description

frizzled class receptor 4

Gene Summary

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]

synonyms
  • frizzled-4
  • WNT receptor frizzled-4
  • frizzled 4, seven transmembrane spanning receptor
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Properties