| Protein Name | angiotensin II receptor, type 1a |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11607 |
| Gene Symbol | Agtr1a |
| UniProt | P29754 (AGTRA_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
193
Total Number of Articles : 307 |
Description |
angiotensin II receptor, type 1a |
| Gene Summary |
Enables angiotensin type I receptor activity. Involved in gene expression; positive regulation of cytokine production; and regulation of blood pressure. Acts upstream of or within several processes, including circulatory system development; regulation of blood pressure; and regulation of smooth muscle cell apoptotic process. Located in endosome and plasma membrane. Is expressed in several structures, including central nervous system; endocrine gland; extraembryonic component; metanephros; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; artery disease (multiple); chronic kidney disease; neurodegenerative disease (multiple); and sarcoidosis. Orthologous to human AGTR1 (angiotensin II receptor type 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |