Protein Name Kruppel-like transcription factor 6
Organism Mus musculus
Gene ID 23849
Gene Symbol

Klf6

UniProt Q8BPQ2 (Q8BPQ2_MOUSE)
Relationships Total Number of functionally related compound(s) : 23
Total Number of Articles : 20
Description

Kruppel-like transcription factor 6

Gene Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of connective tissue replacement. Acts upstream of or within cytokine-mediated signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and peripheral nervous system. Human ortholog(s) of this gene implicated in prostate cancer and stomach cancer. Orthologous to human KLF6 (KLF transcription factor 6). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • Krueppel-like factor 6
  • Kruppel-like factor 6
  • core promoter element binding protein
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Properties