Protein Name hydroxysteroid (17-beta) dehydrogenase 10
Organism Rattus norvegicus
Gene ID 63864
Gene Symbol

Hsd17b10

UniProt O70351 (HCD2_RAT), B0BMW2 (B0BMW2_RAT)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 3
Description

hydroxysteroid (17-beta) dehydrogenase 10

Gene Summary

Enables several functions, including amyloid-beta binding activity; estrogen receptor binding activity; and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Involved in Leydig cell differentiation and cell aging. Located in mitochondrion. Human ortholog(s) of this gene implicated in chromosome Xp11.22 duplication syndrome; pheochromocytoma; and syndromic X-linked intellectual disability type 10. Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • 3-hydroxyacyl-CoA dehydrogenase type-2
  • 17-beta-HSD 10
  • 17-beta-estradiol 17-dehydrogenase
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Properties