Protein Name ciliogenesis associated kinase 1
Organism Homo sapiens
Gene ID 22858
Gene Symbol

CILK1

UniProt Q9UPZ9 (CILK1_HUMAN), A0A024RD59 (A0A024RD59_HUMAN), B3KQG4 (B3KQG4_HUMAN), A0A7I2PIU1 (A0A7I2PIU1_HUMAN)
Relationships Total Number of functionally related compound(s) : 141
Total Number of Articles : 99
Description

ciliogenesis associated kinase 1

Gene Summary

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008]

synonyms
  • serine/threonine-protein kinase ICK
  • MAK-related kinase
  • iciliogenesis associated kinase 1
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Properties