Protein Name | phosphoinositide-3-kinase regulatory subunit 3 |
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Organism | Homo sapiens |
Gene ID | 8503 |
Gene Symbol | PIK3R3 |
UniProt | Q92569 (P55G_HUMAN), Q68CY7 (Q68CY7_HUMAN), Q8N381 (Q8N381_HUMAN), B4DXM8 (B4DXM8_HUMAN), Q7Z3W2 (Q7Z3W2_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
39
Total Number of Articles : 36 |
Description |
phosphoinositide-3-kinase regulatory subunit 3 |
Gene Summary |
Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016] |
synonyms |
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Properties | |