Protein Name Rho guanine nucleotide exchange factor 12
Organism Mus musculus
Gene ID 69632
Gene Symbol

Arhgef12

UniProt F8VQN6 (F8VQN6_MOUSE)
Relationships Total Number of functionally related compound(s) : 21
Total Number of Articles : 18
Description

Rho guanine nucleotide exchange factor 12

Gene Summary

Predicted to enable G protein-coupled receptor binding activity and guanyl-nucleotide exchange factor activity. Involved in regulation of blood pressure. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and skin. Orthologous to human ARHGEF12 (Rho guanine nucleotide exchange factor 12). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • rho guanine nucleotide exchange factor 12
  • Rho guanine nucleotide exchange factor (GEF) 12
  • leukemia-associated Rho guanine-nucleotide exchange factor
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Properties