Protein Name AAA family ATPase SEC18
Organism Saccharomyces cerevisiae S288C
Gene ID 852372
Gene Symbol

SEC18

UniProt P18759 (SEC18_YEAST)
Relationships Total Number of functionally related compound(s) : 19
Total Number of Articles : 32
Description

AAA family ATPase SEC18

Gene Summary

Enables ATP hydrolysis activity; SNARE binding activity; and phosphatidic acid binding activity. Involved in Golgi vesicle transport; SNARE complex disassembly; and vacuole organization. Located in Golgi apparatus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 96. Orthologous to human NSF (N-ethylmaleimide sensitive factor, vesicle fusing ATPase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • AAA family ATPase SEC18
  • YBR080C
  • ANU4
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Properties