Protein Name acyl-CoA thioesterase 8
Organism Homo sapiens
Gene ID 10005
Gene Symbol

ACOT8

UniProt O14734 (ACOT8_HUMAN), A0A494C0N6 (A0A494C0N6_HUMAN)
Relationships Total Number of functionally related compound(s) : 33
Total Number of Articles : 15
Description

acyl-CoA thioesterase 8

Gene Summary

The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. [provided by RefSeq, Oct 2010]

synonyms
  • acyl-coenzyme A thioesterase 8
  • HIV-Nef associated acyl-CoA thioesterase
  • Nef (lentivirus myristoylated factor) associated protein 1
Click to show/hide the synonyms
Properties