| Protein Name | protein tyrosine phosphatase, non-receptor type 6 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 15170 |
| Gene Symbol | Ptpn6 |
| UniProt | P29351 (PTN6_MOUSE), Q3UCJ0 (Q3UCJ0_MOUSE), Q3UB72 (Q3UB72_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
83
Total Number of Articles : 139 |
Description |
protein tyrosine phosphatase, non-receptor type 6 |
| Gene Summary |
Enables several functions, including phosphotyrosine residue binding activity; protein domain specific binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including epididymis development; negative regulation of cytokine production; and negative regulation of inflammatory response to wounding. Acts upstream of or within several processes, including hemopoiesis; negative regulation of protein phosphorylation; and regulation of lymphocyte activation. Located in cell-cell junction. Part of alpha-beta T cell receptor complex. Is active in cytoplasm. Is expressed in several structures, including central nervous system; liver; retina; and thymus primordium. Orthologous to human PTPN6 (protein tyrosine phosphatase non-receptor type 6). [provided by Alliance of Genome Resources, Jun 2025] |
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