| Protein Name | Heat shock protein 22 |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 3772576 |
| Gene Symbol | Hsp22 |
| UniProt | P02515 (HSP22_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
15
Total Number of Articles : 10 |
Description |
Heat shock protein 22 |
| Gene Summary |
Enables identical protein binding activity; protein folding chaperone; and unfolded protein binding activity. Involved in several processes, including determination of adult lifespan; protein folding; and response to heat. Located in mitochondrial matrix. Is expressed in ectoderm. Human ortholog(s) of this gene implicated in cataract 16 multiple types; cataract 9 multiple types; dilated cardiomyopathy 1II; fatal infantile hypertonic myofibrillar myopathy; and myofibrillar myopathy 2. Orthologous to human CRYAA (crystallin alpha A); CRYAB (crystallin alpha B); and HSPB2 (heat shock protein family B (small) member 2). [provided by Alliance of Genome Resources, Jul 2025] |
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