Protein Name neurotrophin 3
Organism Homo sapiens
Gene ID 4908
Gene Symbol

NTF3

UniProt P20783 (NTF3_HUMAN)
Relationships Total Number of functionally related compound(s) : 195
Total Number of Articles : 194
Description

neurotrophin 3

Gene Summary

The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008]

synonyms
  • neurotrophin-3
  • nerve growth factor 2
  • neurotrophic factor
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Properties