| Protein Name | guanylate cyclase 2C |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 2984 |
| Gene Symbol | GUCY2C |
| UniProt | P25092 (GUC2C_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
204
Total Number of Articles : 248 |
Description |
guanylate cyclase 2C |
| Gene Summary |
This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016] |
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| Properties | |