Protein Name fucosyltransferase 8
Organism Homo sapiens
Gene ID 2530
Gene Symbol

FUT8

UniProt Q9BYC5 (FUT8_HUMAN), Q546E0 (Q546E0_HUMAN), A8K8P8 (A8K8P8_HUMAN)
Relationships Total Number of functionally related compound(s) : 91
Total Number of Articles : 89
Description

fucosyltransferase 8

Gene Summary

This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]

synonyms
  • alpha-(1,6)-fucosyltransferase
  • GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase
  • GDP-fucose--glycoprotein fucosyltransferase
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Properties