Protein Name | fucosyltransferase 8 |
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Organism | Homo sapiens |
Gene ID | 2530 |
Gene Symbol | FUT8 |
UniProt | Q9BYC5 (FUT8_HUMAN), Q546E0 (Q546E0_HUMAN), A8K8P8 (A8K8P8_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
91
Total Number of Articles : 89 |
Description |
fucosyltransferase 8 |
Gene Summary |
This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011] |
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